Study: Omega-3 Supplements May Slow Biological Aging

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The Facts

  • A clinical trial conducted by the University of Zurich has found that taking one gram of omega-3 daily for three years reduced biological aging by approximately four months, as measured through epigenetic clocks that analyze DNA methylation patterns.

  • The research, published in Nature Aging on Monday, revealed that combining omega-3 supplements with vitamin D and a regular exercise program of 30 minutes three times a week produced more substantial anti-aging effects and additional health benefits, including a 61% reduction in cancer risk.

  • Additionally, omega-3 supplements alone reduced falls by 11% and infections by 13% among participants — 777 aged 70 and over — demonstrating benefits beyond its effects on biological aging markers.


The Spin

Narrative A

The findings represent a breakthrough in human rejuvenation research, offering an accessible and affordable intervention that could help extend the health span. Combining omega-3 fatty acids, vitamin D, and exercise provides a practical approach to slowing biological aging, with additional benefits for preventing falls, infections, and cancer.


Narrative B

The results should be interpreted cautiously. The study focused on a relatively small, healthy sample of Swiss seniors, and the long-term sustainability of these effects remains unknown. Additionally, no standardized measure of biological aging makes it challenging to prove the intervention's impact on longevity.



Metaculus Prediction




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