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The U.S. Department of Health and Human Services released a policy prohibiting federal support for dangerous gain-of-function research conducted domestically and abroad, fulfilling a Trump executive order aimed at improving the safety and security of biological research.

The U.S. Department of Health and Human Services released a policy prohibiting federal support for dangerous gain-of-function research conducted domestically and abroad, fulfilling a Trump executive order aimed at improving the safety and security of biological research.

The State Department and HHS jointly announced the policy, which also restricts federal funding for research in countries or institutions lacking adequate biosafety, biosecurity and oversight standards.

The State Department and HHS jointly announced the policy, which also restricts federal funding for research in countries or institutions lacking adequate biosafety, biosecurity and oversight standards.

The policy defines dangerous gain-of-function research as work that enhances properties of a biological agent to make it more dangerous. Actual DGOF research is barred, while potential DGOF research remains permitted but subject to a new independent review process.

The policy defines dangerous gain-of-function research as work that enhances properties of a biological agent to make it more dangerous. Actual DGOF research is barred, while potential DGOF research remains permitted but subject to a new independent review process.

HHS Secretary Robert F. Kennedy Jr. said the government would replace "weak oversight with clear, enforceable safeguards," while NIH Director Jay Bhattacharya said the framework ensures the highest-risk research receives "the highest level of scrutiny."

HHS Secretary Robert F. Kennedy Jr. said the government would replace "weak oversight with clear, enforceable safeguards," while NIH Director Jay Bhattacharya said the framework ensures the highest-risk research receives "the highest level of scrutiny."

The policy replaces previous federal oversight frameworks with a risk-based approach that assesses research by potential consequences rather than a limited list of pathogens, requiring researchers and institutions to identify and manage risks before federal funds are awarded.

The policy replaces previous federal oversight frameworks with a risk-based approach that assesses research by potential consequences rather than a limited list of pathogens, requiring researchers and institutions to identify and manage risks before federal funds are awarded.

The policy's release coincided with the publication of a private diary kept by former NIH infectious disease chief Dr. Anthony Fauci, released by Sen. Rand Paul, which included entries noting Fauci was "not a strong advocate" for gain-of-function research.

The policy's release coincided with the publication of a private diary kept by former NIH infectious disease chief Dr. Anthony Fauci, released by Sen. Rand Paul, which included entries noting Fauci was "not a strong advocate" for gain-of-function research.

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