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A UNSW-led review published in the journal Carcinogenesis analyzed peer-reviewed studies from 2017 to 2025 and concluded that nicotine-based e-cigarettes are likely to cause lung and oral cancer.

A UNSW-led review published in the journal Carcinogenesis analyzed peer-reviewed studies from 2017 to 2025 and concluded that nicotine-based e-cigarettes are likely to cause lung and oral cancer.

The review drew on clinical studies, animal experiments and lab data, finding consistent evidence of DNA damage, oxidative stress, tissue inflammation and lung tumors in mice exposed to vape aerosols.

The review drew on clinical studies, animal experiments and lab data, finding consistent evidence of DNA damage, oxidative stress, tissue inflammation and lung tumors in mice exposed to vape aerosols.

Lead author Adjunct Prof. Bernard Stewart said the exact number of cancer cases attributable to vaping remains unclear, noting the assessment is "qualitative and does not involve a numerical estimate of cancer risk or burden."

Lead author Adjunct Prof. Bernard Stewart said the exact number of cancer cases attributable to vaping remains unclear, noting the assessment is "qualitative and does not involve a numerical estimate of cancer risk or burden."

Researchers found that people who both smoke and vape face a fourfold increased risk of developing lung cancer compared to smokers alone, with co-author Assoc. Prof. Freddy Sitas describing many as stuck in "dual-use-limbo."

Researchers found that people who both smoke and vape face a fourfold increased risk of developing lung cancer compared to smokers alone, with co-author Assoc. Prof. Freddy Sitas describing many as stuck in "dual-use-limbo."

Prof. Nick Zwar, chair of the RACGP's Smoking Cessation Guidelines Expert Advisory Group, said it was too early to dismiss vapes as a treatment option, calling the findings "an argument for prospective studies and continuing research."

Prof. Nick Zwar, chair of the RACGP's Smoking Cessation Guidelines Expert Advisory Group, said it was too early to dismiss vapes as a treatment option, calling the findings "an argument for prospective studies and continuing research."

Researchers compared the situation to the century-long delay before smoking was officially linked to lung cancer in 1964, with Sitas urging regulators not to "wait another 80 years to decide what to do."

Researchers compared the situation to the century-long delay before smoking was officially linked to lung cancer in 1964, with Sitas urging regulators not to "wait another 80 years to decide what to do."

E-Cigarettes Likely Cause Lung and Oral Cancer: Study

VapingE-Cigarettes isLikely likelyCause toLung causeand cancer,Oral sayCancer: new findingsStudy

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E-Cigarettes Likely Cause Lung and Oral Cancer: Study

VapingE-Cigarettes isLikely likelyCause toLung causeand cancer,Oral sayCancer: new findingsStudy

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