BBC News

Single vaccine could protect against all coughs, colds and flus, researchers say

Science

Science.Aea1260

Stanford Medicine

One vaccine may provide broad protection against many respiratory infections and allergens

Bioengineer.org

Single Vaccine Could Offer Wide Protection Against Multiple Respiratory

South China Morning Post

Scientists test universal vaccine for cold, flu, Covid and allergies

The Independent

Scientists develop universal vaccine to protect against allergies, cold and flu

Sky News

Universal vaccine for cold, flu, COVID and allergies moves a step closer, scientists say

Nature

Universal vaccine protects mice against multiple pathogens

MIT Technology Review

Heres why we dont have a cold vaccine. Yet.

LabWaggoner

Harnessing mucosal immunity for protective vaccines

LindaGGriffith1

Metaculus

Intranasal SARS-CoV-2 Vaccine Authorized

Robert F. Kennedy Jr.

Bill Cassidy

Mehmet Oz

Jay Bhattacharya

Michael Osterholm

Jim O'Neill

Jason M. Goldman

Jesse L. Goodman

Kevin A. Ault

IDSA

Diana DeGette

Caitlin Rivers

Andrew Racine

Robert Goldstein

WLBT3

West Coast Health Alliance

Sean O'Leary

UC Berkeley School of Public Health

Marty Makary

"This decision protects children, respects families, and rebuilds trust in public health."

"This [2026] decision recommits HHS to all three [transparency, rigorous science, and respect for families]."

"This decision commits NIH, CDC, and FDA to gold standard science, greater transparency, and ongoing reassessment as new data emerge."

"No family will lose access.This [2026] framework empowers parents and physicians to make individualized decisions based on risk, while maintaining strong protection against serious disease."

"The data support a more focused schedule that protects children from the most serious infectious diseases while improving clarity, adherence, and public confidence."

“I think that a reduced schedule is going to endanger children and lay the groundwork for a resurgence in preventable disease.”

“Changing the pediatric vaccine schedule based on no scientific input on safety risks and little transparency will cause unnecessary fear for patients and doctors, and will make America sicker.”

"This wildly irresponsible decision will put lives at risk."

“There will be more diseases, more infection, more hospitalizations.”

Will Secretary Kennedy's U.S. Childhood Vaccine Schedule Overhaul Risk Public Health?

Researchers at Stanford University developed an intranasal vaccine that provided protection in mice for at least three months against multiple respiratory threats including SARS-CoV-2, other coronaviruses, bacterial infections such as Staphylococcus aureus and Acinetobacter baumannii, and allergens like house dust mites.

Researchers at Stanford University developed an intranasal vaccine that provided protection in mice for at least three months against multiple respiratory threats including SARS-CoV-2, other coronaviruses, bacterial infections such as Staphylococcus aureus and Acinetobacter baumannii, and allergens like house dust mites.

The vaccine works by mimicking cellular communication signals between immune cells rather than targeting specific pathogen antigens, representing what researchers describe as a departure from the principle by which vaccines have operated since Edward Jenner's pioneering work in the late 18th Century.

The vaccine works by mimicking cellular communication signals between immune cells rather than targeting specific pathogen antigens, representing what researchers describe as a departure from the principle by which vaccines have operated since Edward Jenner's pioneering work in the late 18th Century.

The vaccine formulation combines toll-like receptor 4 and 7/8 ligands with ovalbumin, a model antigen, and is delivered as a nasal spray that leaves alveolar macrophages in the lungs in a heightened state of readiness, according to the study published in the journal Science.

The vaccine formulation combines toll-like receptor 4 and 7/8 ligands with ovalbumin, a model antigen, and is delivered as a nasal spray that leaves alveolar macrophages in the lungs in a heightened state of readiness, according to the study published in the journal Science.

Vaccinated mice showed a 100-to-1,000-fold reduction in viral loads in their lungs and mounted rapid pathogen-specific immune responses in as little as three days, compared to the typical two-week period in unvaccinated animals, researchers reported.

Vaccinated mice showed a 100-to-1,000-fold reduction in viral loads in their lungs and mounted rapid pathogen-specific immune responses in as little as three days, compared to the typical two-week period in unvaccinated animals, researchers reported.

Professor Bali Pulendran estimates that with sufficient funding, a universal respiratory vaccine for humans might be available in five to seven years, following Phase I safety trials and controlled human challenge studies to evaluate efficacy.

Professor Bali Pulendran estimates that with sufficient funding, a universal respiratory vaccine for humans might be available in five to seven years, following Phase I safety trials and controlled human challenge studies to evaluate efficacy.

Experts including Professor Jonathan Ball from Liverpool School of Tropical Medicine cautioned that keeping the immune system on high alert could potentially trigger unwelcome side effects, while Professor Daniela Ferreira from University of Oxford described the research as potentially marking a major step forward.

Experts including Professor Jonathan Ball from Liverpool School of Tropical Medicine cautioned that keeping the immune system on high alert could potentially trigger unwelcome side effects, while Professor Daniela Ferreira from University of Oxford described the research as potentially marking a major step forward.

Stanford Develops Nasal Spray Vaccine for Multiple Threats

Stanford Develops Nasal Spray Vaccine for Multiple Threats

The Controversies

Jr.

Makary

Bhattacharya

Oz

O'Neill

Rivers

Cassidy

Goodman

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Stanford Develops Nasal Spray Vaccine for Multiple Threats

Stanford Develops Nasal Spray Vaccine for Multiple Threats

The Controversies

Jr.

Makary

Bhattacharya

Oz

O'Neill

Rivers

Cassidy

Goodman

Go Deeper

Articles on this story

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