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A University of Cambridge study involving nearly 125,000 women found that menopause is associated with a loss of grey matter in brain regions including the hippocampus, entorhinal cortex and anterior cingulate cortex, which are areas involved in memory, emotion and attention.

A University of Cambridge study involving nearly 125,000 women found that menopause is associated with a loss of grey matter in brain regions including the hippocampus, entorhinal cortex and anterior cingulate cortex, which are areas involved in memory, emotion and attention.

Women account for approximately two thirds of people living with Alzheimer's disease in the UK, and researchers suggest that hormonal changes during menopause may partly explain why women are at greater risk of dementia than men.

Women account for approximately two thirds of people living with Alzheimer's disease in the UK, and researchers suggest that hormonal changes during menopause may partly explain why women are at greater risk of dementia than men.

The study found that hormone replacement therapy did not appear to prevent grey matter loss in post-menopausal women, though women on HRT showed slightly faster reaction times compared to those not taking the treatment.

The study found that hormone replacement therapy did not appear to prevent grey matter loss in post-menopausal women, though women on HRT showed slightly faster reaction times compared to those not taking the treatment.

Post-menopausal women reported higher levels of anxiety, depression, insomnia and tiredness compared to pre-menopausal women. Women on HRT reported the highest levels of tiredness among all groups studied.

Post-menopausal women reported higher levels of anxiety, depression, insomnia and tiredness compared to pre-menopausal women. Women on HRT reported the highest levels of tiredness among all groups studied.

The average age of menopause onset among study participants was approximately 49.5 years, and women prescribed HRT typically began treatment around age 49, according to data from the UK Biobank cohort study conducted between 2006 and 2010.

The average age of menopause onset among study participants was approximately 49.5 years, and women prescribed HRT typically began treatment around age 49, according to data from the UK Biobank cohort study conducted between 2006 and 2010.

Researchers noted that women prescribed HRT often had pre-existing mental health symptoms before starting treatment, and emphasized that lifestyle factors such as regular exercise, not smoking and limiting alcohol can help reduce dementia risk.

Researchers noted that women prescribed HRT often had pre-existing mental health symptoms before starting treatment, and emphasized that lifestyle factors such as regular exercise, not smoking and limiting alcohol can help reduce dementia risk.

Menopause Linked to Brain Grey Matter Loss, Study Finds

Menopause linkedLinked to Alzheimer's-likeBrain brainGrey changesMatter Loss, Study Finds

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Menopause Linked to Brain Grey Matter Loss, Study Finds

Menopause linkedLinked to Alzheimer's-likeBrain brainGrey changesMatter Loss, Study Finds

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