Blood cancer therapy reverses incurable leukaemia in some patients
BBC News5 days
Gene-edited therapy BE-CAR7 represents a monumental breakthrough in cancer treatment, achieving 82% deep remission rates for previously incurable T-cell leukemia. This off-the-shelf treatment uses base editing to transform donor immune cells into cancer-fighting weapons, offering real hope where only palliative care existed before.
While BE-CAR7 shows promise, the reality remains sobering: only 64% of patients remain disease-free, and outcomes were not as hoped for some children in these intense, difficult treatments. The therapy requires wiping out the entire immune system, leaving patients vulnerable to life-threatening infections during recovery.
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