News Medical

Off-label ketamine use for chronic pain lacks scientific basis

UNSW Sydney

No clear benefit: Ketamine use for chronic pain under scrutiny

EuroNews

No evidence that ketamine helps with chronic pain, major review finds

Eurekalert

Ketamine use in chronic pain unsupported by evidence

Cochrane Library

Ketamine and other NMDA receptor antagonists for chronic pain

Onlinelibrary

Med4.4

Healthline

Ketamine Therapy for Pain Management: Benefits, Process, and Risks

The review found no clear evidence of benefit for ketamine in chronic pain treatment and identified an increased risk of adverse effects such as delusions, delirium, paranoia, nausea, and vomiting.</span

The review found no clear evidence of benefit for ketamine in chronic pain treatment and identified an increased risk of adverse effects such as delusions, delirium, paranoia, nausea, and vomiting.

Evidence quality was rated low to very low certainty due to small study sizes and poor methodological quality, with researchers noting significant uncertainty about ketamine's effectiveness.</span

Evidence quality was rated low to very low certainty due to small study sizes and poor methodological quality, with researchers noting significant uncertainty about ketamine's effectiveness.

The analysis included various dosing strategies including intravenous, oral and topical ketamine administration across multiple chronic pain conditions but found no clear evidence of benefit in any specific condition or dose.</span

The analysis included various dosing strategies including intravenous, oral and topical ketamine administration across multiple chronic pain conditions but found no clear evidence of benefit in any specific condition or dose.

No studies in the review reported on whether ketamine reduced depressive symptoms or opioid use, despite ketamine often being proposed for patients with depressive symptoms or opioid tolerance.</span

No studies in the review reported on whether ketamine reduced depressive symptoms or opioid use, despite ketamine often being proposed for patients with depressive symptoms or opioid tolerance.

Researchers warned against rushing into widespread ketamine use without strong evidence, drawing parallels to past mistakes with opioid medications that were developed for acute pain but applied to chronic conditions.</span

Researchers warned against rushing into widespread ketamine use without strong evidence, drawing parallels to past mistakes with opioid medications that were developed for acute pain but applied to chronic conditions.

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UNSW Sydney #

EuroNews #

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Cochrane Library #

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Healthline #

No evidence that ketamine helps with chronic pain

Diseases & conditions

Health

Pharmaceuticals

The evidence isn't strong enough to definitively rule out ketamine's potential benefits for chronic pain sufferers. With limited high-quality studies and very low certainty ratings, there's still significant uncertainty about whether ketamine could help patients.

The evidence isn't strong enough to definitively rule out ketamine's potential benefits for chronic pain sufferers. With limited high-quality studies and very low certainty ratings, there's still significant uncertainty about whether ketamine could help patients.

Ketamine Shows No Clear Benefit for Chronic Pain Treatment

Ketamine Shows No Clear Benefit for Chronic Pain Treatment

Ketamine Shows No evidenceClear thatBenefit ketaminefor helpsChronic withPain chronic painTreatment

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Ketamine Shows No Clear Benefit for Chronic Pain Treatment

Ketamine Shows No evidenceClear thatBenefit ketaminefor helpsChronic withPain chronic painTreatment

The Spin

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