PHYS

Why you may get future vaccines via dental floss

Nature

Floss-based vaccination targets the gingival sulcus for mucosal and systemic immunization

Science

Engineers Transform Dental Floss Needle Free Vaccin

ScienceAlert

New Kind of Dental Floss Could Replace Vaccine Needles, Study Finds

Decisions in Dentistry

Study Explores Needle-Free Vaccines via Floss

Livescience.Com

Scientists gave mice flu vaccines by flossing their tiny teeth  and it worked

Interesting Engineering

Floss-based flu vaccine triggers full immunity in mouse study

ZME Science

Scientists transform flossing into needle-free vaccine

Vice

Dental Floss Could Be the Future of Vaccines

Metaculus

Intranasal SARS-CoV-2 Vaccine Authorized

<span>The junctional epithelium is a thin, permeable tissue layer in the gum pocket that lacks barrier features found in other epithelial tissues, allowing immune cells to move freely and making it suitable for vaccine absorption.</span

The junctional epithelium is a thin, permeable tissue layer in the gum pocket that lacks barrier features found in other epithelial tissues, allowing immune cells to move freely and making it suitable for vaccine absorption.

<span>In mouse studies, floss-based vaccination with inactivated influenza virus provided complete protection against lethal flu infection, with all 50 vaccinated mice surviving exposure while unvaccinated mice died.</span

In mouse studies, floss-based vaccination with inactivated influenza virus provided complete protection against lethal flu infection, with all 50 vaccinated mice surviving exposure while unvaccinated mice died.

<span>The floss delivery method stimulated antibody production in both systemic circulation and mucosal surfaces including the nose, lungs, saliva, and bone marrow, indicating robust immune activation across multiple organs.</span

The floss delivery method stimulated antibody production in both systemic circulation and mucosal surfaces including the nose, lungs, saliva, and bone marrow, indicating robust immune activation across multiple organs.

<span>Human feasibility testing with 27 volunteers using fluorescent dye-coated floss picks showed approximately 60% of the material successfully reached the gingival sulcus target area.</span

Human feasibility testing with 27 volunteers using fluorescent dye-coated floss picks showed approximately 60% of the material successfully reached the gingival sulcus target area.

<span>The research tested multiple vaccine types including proteins, inactivated viruses, peptide-presenting nanoparticles, and messenger RNA, with all formulations producing strong immune responses in the animal model.</span

The research tested multiple vaccine types including proteins, inactivated viruses, peptide-presenting nanoparticles, and messenger RNA, with all formulations producing strong immune responses in the animal model.

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Floss-Based Vaccine Delivery Advances Toward Clinical Trials

Health

Science & technology

Vaccination

The technology raises serious concerns about consent and coercion in mass vaccination campaigns. If floss-based vaccines become widespread, they could be administered without public awareness or proper oversight. The potential for adding vaccines to everyday products like toothpaste creates alarming possibilities for bypassing individual health autonomy.

<span>The technology raises serious concerns about consent and coercion in mass vaccination campaigns. If floss-based vaccines become widespread, they could be administered without public awareness or proper oversight. The potential for adding vaccines to everyday products like toothpaste creates alarming possibilities for bypassing individual health autonomy.</span>

Scientists Develop Dental Floss Vaccine Delivery Method

Scientists Develop Dental Floss Vaccine Delivery Method

Scientists Develop Dental Floss-Based Vaccine Delivery Advances Toward Clinical TrialsMethod

The Spin

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Scientists Develop Dental Floss Vaccine Delivery Method

Scientists Develop Dental Floss-Based Vaccine Delivery Advances Toward Clinical TrialsMethod

The Spin

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