MIT Technology Review

Researchers announce babies born from a trial of three-person IVF

EuroNews

Healthy babies born in UK using DNA from 3 people to prevent hereditary diseases

Guardian

Eight healthy babies born after IVF using DNA from three people

BBC News

Babies from three people's DNA prevents heriditary disease

The Conversation

Babies born with DNA from three people hailed as breakthrough  but questions remain

Mitochondrial disease: Healthy babies born in Britain after scientists used DNA from three people to avoid genetic disease

The Times

Three-parent babies are born in UK via pioneering IVF treatment

Nature

Landmark study: three-person IVF leads to eight healthy children

The Telegraph

First three-parent babies found healthy in scientific breakthrough

Ninds

Mitochondrial Disorder

Daily Mail

Eight babies have been born in Britain using a new three-person IVF technique designed to prevent hereditary diseases

Jack Tseng

Eriona Hysolli

Colossal Biosciences Inc.

Beth Shapiro

Joseph Frederickson

Ben Lamm

Brian Klaas

George Church

Ben Mezrich

Mary Beth Griggs

Jeremy Austin

Metaculus

"[N]o one is actually going to bring mammoths back."

"Is this [the restoration of woolly mammoths] going to happen anytime soon? The answer is absolutely not."

"Mammoth de-extinction is more about media attention for the scientists and less about doing serious science."

"It feels to me that a mammoth is a long way in the future."

"I think it's [bringing back woolly mammoth] definitely within the technology."

"In 2028, if all goes according to plan, a six-foot-five narcoleptic scientist with a bushy white beard will resurrect the first living woolly mammoth in 4,000 years."

"I think the first engineered elephant will be the major milestone and that may be consistent with Ben's (Lamm) prediction of six years from 2021."

"That timeline [2028 for the birth of the first mammoth calves] hasn't changed."

"We have set a date of late 2028 for our first mammoth and we are on track."

Will the Woolly Mammoth Be Resurrected by 2028?

<span>The procedure involves fertilizing eggs from both the mother and a donor with the father's sperm, then transferring the parents' nuclear DNA into the donor's egg containing healthy mitochondria, creating embryos with less than 1% donor DNA.</span

New Scientist

The procedure involves fertilizing eggs from both the mother and a donor with the father's sperm, then transferring the parents' nuclear DNA into the donor's egg containing healthy mitochondria, creating embryos with less than 1% donor DNA.

<span>Seven women gave birth to eight children including one set of twins after 22 families underwent the treatment at Newcastle Fertility Centre, with all babies showing no signs of mitochondrial disease and meeting developmental milestones.</span

Seven women gave birth to eight children including one set of twins after 22 families underwent the treatment at Newcastle Fertility Centre, with all babies showing no signs of mitochondrial disease and meeting developmental milestones.

<span>Blood tests revealed five babies had no detectable mutated mitochondrial DNA while three showed 5-20% levels, which remains below the 80% threshold typically required to cause disease symptoms.</span

Al Jazeera

Blood tests revealed five babies had no detectable mutated mitochondrial DNA while three showed 5-20% levels, which remains below the 80% threshold typically required to cause disease symptoms.

<span>The technique became legal in the UK in 2015 following parliamentary approval, with the Human Fertilisation and Embryology Authority granting Newcastle the first license in 2017 to perform the procedure.</span

The technique became legal in the UK in 2015 following parliamentary approval, with the Human Fertilisation and Embryology Authority granting Newcastle the first license in 2017 to perform the procedure.

<span>Mitochondrial diseases affect approximately one in 5,000 newborns and can cause severe symptoms including seizures, muscle weakness, organ failure and early death, with no current cure available for these inherited conditions.</span

Mitochondrial diseases affect approximately one in 5,000 newborns and can cause severe symptoms including seizures, muscle weakness, organ failure and early death, with no current cure available for these inherited conditions.

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<h2></h2>

Health

Science & technology

The results raise serious concerns about safety and transparency after nearly a decade of development. Only eight babies from 22 families hardly justifies the massive investment, and three children still carry mutated DNA that could cause future problems. The lack of public updates until now shows troubling secrecy.

<span>The results raise serious concerns about safety and transparency after nearly a decade of development. Only eight babies from 22 families hardly justifies the massive investment, and three children still carry mutated DNA that could cause future problems. The lack of public updates until now shows troubling secrecy.</span>

NPR Online News

Mitochondrial disease prevented with donated genes : Shots

UK Reports First 8 Babies Born Using Three-Person DNA Technique

UK Reports First 8 Babies Born Using Three-Person DNA Technique

EightUK healthyReports babiesFirst born8 afterBabies IVFBorn usingUsing Three-Person DNA from three peopleTechnique

The Spin

The Controversies

Griggs

Frederickson

Austin

Shapiro

Tseng

Klaas

Church

Hysolli

Lamm

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UK Reports First 8 Babies Born Using Three-Person DNA Technique

EightUK healthyReports babiesFirst born8 afterBabies IVFBorn usingUsing Three-Person DNA from three peopleTechnique

The Spin

The Controversies

Griggs

Frederickson

Austin

Shapiro

Tseng

Klaas

Church

Hysolli

Lamm

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