Guardian

Surgeons in California perform first ever successful bladder transplant

Daily Mail

World's first bladder transplant hailed as 'groundbreaking moment in medical history' - op gives hope to cancer patients

Independent

World-first bladder transplant a ‘historic’ success four years in the making

New York Post

Groundbreaking bladder transplant gives cancer survivor hope: ‘I was a ticking time bomb’

Surgeons from UCLA Health and the USC Institute of Urology performed the world’s first successful human bladder transplant on May 4 in an eight-hour procedure at the Ronald Reagan UCLA Medical Center.

UCLA

Surgeons from UCLA Health and the USC Institute of Urology performed the world’s first successful human bladder transplant on May 4 in an eight-hour procedure at the Ronald Reagan UCLA Medical Center.

The recipient, Oscar Larrainzar, a 41-year-old Los Angeles resident, had lost most of his bladder to a rare form of cancer and had both kidneys removed as part of the treatment, leaving him dependent on dialysis for seven years.&nbsp;

The recipient, Oscar Larrainzar, a 41-year-old Los Angeles resident, had lost most of his bladder to a rare form of cancer and had both kidneys removed as part of the treatment, leaving him dependent on dialysis for seven years. 

According to releases from UCLA and USC, the procedure first involved transplanting a new kidney, followed by a new bladder, which was then connected via a new technique pioneered by the surgeons.&nbsp;

Keckmedicine

According to releases from UCLA and USC, the procedure first involved transplanting a new kidney, followed by a new bladder, which was then connected via a new technique pioneered by the surgeons. 

The surgical technique was developed over four years of research, including numerous practice surgeries on animals and deceased donors and overcoming challenges related to the complex vascular structure of the pelvic area.

The surgical technique was developed over four years of research, including numerous practice surgeries on animals and deceased donors and overcoming challenges related to the complex vascular structure of the pelvic area.

Speaking on the successful transplant, Dr. Inderbir Gill of USC described the operation as a “historic moment in medicine.” Meanwhile, Dr. Nima Nassiri of UCLA said it was “exciting” to pioneer a new treatment option for those with non-functioning bladders.

Speaking on the successful transplant, Dr. Inderbir Gill of USC described the operation as a “historic moment in medicine.” Meanwhile, Dr. Nima Nassiri of UCLA said it was “exciting” to pioneer a new treatment option for those with non-functioning bladders.

The surgical teams plan on performing bladder transplants in four more patients as part of a clinical trial to evaluate outcomes, such as bladder capacity and any potential complications, before pursuing a larger trial.

New York Times

The surgical teams plan on performing bladder transplants in four more patients as part of a clinical trial to evaluate outcomes, such as bladder capacity and any potential complications, before pursuing a larger trial.

Guardian #1

Daily Mail #1

Independent #1

New York Post #1

The recipient, Oscar Larrainzar, a 41-year-old Los Angeles father of four, had lost most of his bladder to cancer and had both kidneys removed, leaving him dependent on dialysis for seven years before receiving the groundbreaking combined kidney-bladder transplant.</span

Guardian #2183

Daily Mail #4503

The recipient, Oscar Larrainzar, a 41-year-old Los Angeles father of four, had lost most of his bladder to cancer and had both kidneys removed, leaving him dependent on dialysis for seven years before receiving the groundbreaking combined kidney-bladder transplant.

The complex procedure involved first transplanting the kidney, followed by the bladder, and then connecting the new kidney to the transplanted bladder, resulting in immediate kidney function improvement and proper urine drainage without the need for post-surgery dialysis.</span

Independent #4588

The complex procedure involved first transplanting the kidney, followed by the bladder, and then connecting the new kidney to the transplanted bladder, resulting in immediate kidney function improvement and proper urine drainage without the need for post-surgery dialysis.

Prior to this breakthrough, patients with non-functioning bladders typically relied on having portions of their intestines repurposed for urinary function, a procedure that leads to complications in up to 80 percent of cases, including infections, kidney failure, and digestive issues.</span

Prior to this breakthrough, patients with non-functioning bladders typically relied on having portions of their intestines repurposed for urinary function, a procedure that leads to complications in up to 80 percent of cases, including infections, kidney failure, and digestive issues.

The surgical technique was developed over four years of research, including numerous practice surgeries on animals and deceased donors, overcoming challenges related to the complex vascular structure of the pelvic area.</span

New York Post #2438

The surgical technique was developed over four years of research, including numerous practice surgeries on animals and deceased donors, overcoming challenges related to the complex vascular structure of the pelvic area.

The surgical team plans to perform bladder transplants in four more patients as part of a clinical trial to evaluate outcomes and bladder capacity before pursuing a larger trial to expand its use for carefully selected patients.</span

The surgical team plans to perform bladder transplants in four more patients as part of a clinical trial to evaluate outcomes and bladder capacity before pursuing a larger trial to expand its use for carefully selected patients.

While the initial surgery shows promise, significant uncertainties remain about long-term outcomes and rejection risks. The procedure requires lifelong immunosuppression medication, limiting eligible candidates to those already on transplant medications or requiring multiple organ transplants. The true success of this pioneering surgery can only be determined after extensive clinical trials and long-term monitoring.

While the initial surgery shows promise, significant uncertainties remain about long-term outcomes and rejection risks. The procedure requires lifelong immunosuppression medication, limiting eligible candidates to those already on transplant medications or requiring multiple organ transplants. The true success of this pioneering surgery can only be determined after extensive clinical trials and long-term monitoring.

UCLA #

Worlds first human bladder transplant performed at UCLA

Surgeons Complete World's First Human Bladder Transplant

Headlines

Science & technology

Health

The groundbreaking bladder transplant represents a revolutionary advancement in organ transplantation, offering a more natural solution for patients with terminal bladder conditions. This procedure delivers a normal urinary reservoir and circumvents the severe complications associated with current intestinal-based treatments. The successful operation opens new doors for millions suffering from bladder dysfunction worldwide.

The groundbreaking bladder transplant represents a revolutionary advancement in organ transplantation, offering a more natural solution for patients with terminal bladder conditions. This procedure delivers a normal urinary reservoir and circumvents the severe complications associated with current intestinal-based treatments. The successful operation opens new doors for millions suffering from bladder dysfunction worldwide.

Surgeons Complete World's First Human Bladder Transplant

Surgeons Complete World's First Human Bladder Transplant

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Surgeons Complete World's First Human Bladder Transplant

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