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Snapshot 7:Thu, Nov 7, 2024 10:27:22 PM GMT last edited by KateHennig

Study: Aggressive Cancer Can be Treated by Targeting Rogue DNA

Study: Aggressive Cancer Can be Treated by Targeting Rogue DNA

Above: Radiologist Fredric Pedulla shows a nodule on a lung scan of a smoking person for the Acapulco experimentation in Ajaccio on December 16, 2021, on the French Mediterranean island of Corsica. Image copyright: Pascal Pochard-Casabianca/Contributor/AFP via Getty Images

The Facts

  • Researchers from the UK and US have found that treating the most aggressive cancers should focus on targeting extrachromosomal DNA (ecDNA), which are "rogue" DNA fragments that help cancerous tumors flourish and become chemotherapy-resistant.

  • They found ecDNA is present in over 17% of analyzed tumors, particularly in aggressive forms of breast, brain, and lung cancers.


The Spin

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