In a new study, researchers have discovered a major driver of inflammatory bowel disease (IBD), which encompasses conditions such as Crohn's disease and ulcerative colitis, by finding a basis for inflammation in immune cells.
Researchers at the Francis Crick Institute in London found that a section of DNA found in immune cells, known as macrophages, boosted a gene known as ETS2, which is central for the inflammation properties of macrophages.
This discovery could change the lives of those living with IBD around the world, as we have finally found an effective treatment. While clinical trials are needed to rigorously test the drugs used to quell inflammation, there is finally hope on the horizon for those that suffer from these common and chronic conditions.
Scientists have been perplexed by the explosion in autoimmune disorders such as IBD. Autoimmune disease has been described as a silent epidemic, and may be connected our changing lifestyles and the chemicals we are exposed to in the modern age. Given that these diseases are so expensive to treat, let's focus on fixing our toxic environments before resorting to expensive treatments.